The exodus of Venezuelans is the largest in the recent history of Latin America and the Caribbean. As of November 2020, more than 5.4 million refugees and migrants from Venezuela are outside their country of origin, with 4.6 million in the region alone. 

In this context, the Refugee and Migrant Response Plan 2021 is the result of field-driven planning, bringing together 159 appealing organizations in 17 countries, in consultation with host governments, civil society and faith-based organizations, local communities, donors, as well as the refugees and migrants themselves, with the common objective of addressing the overarching humanitarian, protection and socioeconomic integration needs of refugees and migrants from Venezuela.